Reaction Summary

Reaction from 5′ diphosphate end (p(pN)) to guanylylated 5′ end (cap G) (Gpp(pN))

Reaction details:

Reaction type level 1: 5ʹ-5ʹ guanylylation
Reaction type level 2: nucleotide addition
Reaction type level 3: group addition
Input group: *P(=O)(O)OP(=O)(O)O
Output group: [O-]P(=O)(O)OC[C@@H]3O[C@H](n2cnc1c2N=C(N)NC1=O)[C@@H](O)[C@H]3O*
Introduced group name: guanylyl
Introduced group type: nucleotide
Site: phosphate
Atom address: O5'.P3
Modification level: 0

Enzymes that catalyse this reaction:

Acronym Full name Organism
Ceg1 GTP-RNA guanylyltransferase Saccharomyces cerevisiae
HCAP1 RNA-capping enzyme Homo sapiens
Image with reaction

Image with reaction

Image with reaction

Entry added on: 2012-06-22 16:12:59.475337, by a user: magda