Reaction Summary

Reaction from 5-methoxycarbonylmethyluridine (mcm5U) to 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U)

Reaction details:

Reaction type level 1: O/S exchange
Reaction type level 2: O/S exchange
Reaction type level 3: group exchange
Input group: O
Output group: *=S
Introduced group name: thio
Introduced group type: sulphur
Site: base/endocyclic
Atom address: C2
Modification level: 3

Enzymes that catalyse this reaction:

Acronym Full name Organism
Ncs2 Cytoplasmic tRNA 2-thiolation protein 2 Saccharomyces cerevisiae
Ncs6 Cytoplasmic tRNA 2-thiolation protein 1 Saccharomyces cerevisiae
TrmU Mitochondrial tRNA-specific 2-thiouridylase 1 Homo sapiens
 
Image with reaction


Image with reaction

Image with reaction

Last modification of this entry: 2012-01-11 10:57:18.531777
Edited by a user: magda
Edited content: Changed papers.