Reaction Summary

Reaction from 2′-O-methyluridine (Um) to 5-carboxymethylaminomethyl-2′-O-methyluridine (cmnm5Um)

Reaction details:

Reaction type level 1: carboxymethylaminomethylation
Reaction type level 2: aminoalkylation
Reaction type level 3: group addition
Input group: H
Output group: *CNCC(=O)O
Introduced group name: carboxymethylaminomethyl
Introduced group type: aminoalkyl
Site: base/endocyclic
Atom address: C5
Modification level: 2

Enzymes that catalyse this reaction:

Acronym Full name Organism
MnmE tRNA uridine(34) 5-carboxymethylaminomethyl synthesis GTPase Escherichia coli
MnmE tRNA modification GTPase MnmE Chlorobium tepidum
MnmE tRNA modification GTPase MnmE Nostoc sp.
MnmE tRNA modification GTPase MnmE Thermotoga maritima
MnmG tRNA uridine(34) 5-carboxymethylaminomethyl synthesis enzyme Escherichia coli
MnmG tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG Chlorobium tepidum
MnmG tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG Aquifex aeolicus
 
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Image with reaction

Last modification of this entry: 2012-08-22 16:06:08.529227
Edited by a user: magda
Edited content: Changed type.