Reaction Summary

Reaction from uridine (U) to 2-thiouridine (s2U)

Reaction details:

Reaction type level 1: O/S exchange
Reaction type level 2: O/S exchange
Reaction type level 3: group exchange
Input group: O
Output group: *=S
Introduced group name: thio
Introduced group type: sulphur
Site: base/endocyclic
Atom address: C2
Modification level: 1

Enzymes that catalyse this reaction:

Acronym Full name Organism
MnmA tRNA 2-thiouridine(34) synthase Escherichia coli
Mtu1 Mitochondrial tRNA-specific 2-thiouridylase 1 Saccharomyces cerevisiae
Ncs2 Cytoplasmic tRNA 2-thiolation protein 2 Saccharomyces cerevisiae
Ncs6 Cytoplasmic tRNA 2-thiolation protein 1 Saccharomyces cerevisiae
TrmU Mitochondrial tRNA-specific 2-thiouridylase 1 Homo sapiens
Image with reaction

Image with reaction

Image with reaction

Last modification of this entry: 2012-01-31 14:25:14.405672
Edited by a user: magda
Edited content: Changed comment.