Reaction Summary

Reaction from guanylylated 5′ end (cap G) (Gpp(pN)) to 7-methylguanosine cap (cap 0) (m7Gpp(pN))

Reaction details:

Reaction type level 1: methylation
Reaction type level 2: alkylation
Reaction type level 3: group addition
Input group: none
Output group: *C
Introduced group name: methyl
Introduced group type: hydrocarbon
Site: base/endocyclic
Atom address: N7
Modification level: 3

Enzymes that catalyse this reaction:

Acronym Full name Organism
Abd1 RNA cap guanine-N7 methyltransferase Saccharomyces cerevisiae
Hcm1 RNA cap guanine-N7 methyltransferase Homo sapiens
Image with reaction

Image with reaction

Image with reaction

Entry added on: 2012-06-22 16:13:34.869126, by a user: magda