Reaction Summary

Reaction from adenosine (A) to N6-methyladenosine (m6A)

Reaction details:

Reaction type level 1: methylation
Reaction type level 2: alkylation
Reaction type level 3: group addition
Input group: H
Output group: *C
Introduced group name: methyl
Introduced group type: hydrocarbon
Site: base/exocyclic
Atom address: N6
Modification level: 1

Enzymes that catalyse this reaction:

Acronym Full name Organism
ErmAM rRNA adenine N-6-methyltransferase Streptococcus pneumoniae
ErmBC rRNA adenine N-6-methyltransferase Escherichia coli
ErmC' rRNA adenine N-6-methyltransferase Bacillus subtilis
Ime4 N6-adenosine-methyltransferase IME4 Saccharomyces cerevisiae
METTL14 Homo sapiens
METTL3 N6-adenosine-methyltransferase 70 kDa subunit Homo sapiens
RlmF Ribosomal RNA large subunit methyltransferase F Escherichia coli
RlmJ Ribosomal RNA large subunit methyltransferase J Escherichia coli
RsmA Ribosomal RNA small subunit methyltransferase A Escherichia coli
RsmA Dimethyladenosine transferase Saccharomyces cerevisiae
RsmA Ribosomal RNA small subunit methyltransferase A Thermus thermophilus
TrmM tRNA (adenosine(37)-N6)-methyltransferase Escherichia coli
 
Image with reaction


Image with reaction

Image with reaction

Last modification of this entry: 2011-09-14 13:52:29.925779
Edited by a user: magda
Edited content: Changed kingdom and rna.