Reaction Summary

Reaction from adenosine (A) to 1-methyladenosine (m1A)

Reaction details:

Reaction type level 1: methylation
Reaction type level 2: alkylation
Reaction type level 3: group addition
Input group: none
Output group: *C
Introduced group name: methyl
Introduced group type: hydrocarbon
Site: base/endocyclic
Atom address: N1
Modification level: 1

Enzymes that catalyse this reaction:

Acronym Full name Organism
Bmt2 Saccharomyces cerevisiae
KamB rRNA adenine N-1-methyltransferase Streptomyces sp. DSM 40477
NpmA rRNA adenine N-1-methyltransferase Escherichia coli
Rrp8 Ribosomal RNA-processing protein 8 Saccharomyces cerevisiae
TRMT10C tRNA methyltransferase 10 C, mitochondrial Homo sapiens
Trm61 tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61 Saccharomyces cerevisiae
TrmI tRNA (adenine(57)-N(1)/adenine(58)-N(1))-methyltransferase TrmI Pyrococcus abyssi
TrmI tRNA (adenine(58)-N(1))-methyltransferase TrmI Thermus thermophilus
TrmI tRNA (adenine(58)-N(1))-methyltransferase TrmI Mycobacterium tuberculosis
TrmK tRNA (adenine(22)-N(1))-methyltransferase Bacillus subtilis
Trmt61A tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A Homo sapiens
Trmt61B tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial Homo sapiens
Image with reaction

Image with reaction

Image with reaction

Last modification of this entry: 2011-09-14 13:49:48.438162
Edited by a user: magda
Edited content: Changed kingdom and rna.