"2′-O-Methyl Thiomethyl Modifications in Hammerhead Ribozymes"

Alexander Karpeisky , Carolyn Gonzalez, Alex B. Burgin, Nassim Usman & Leonid Beigelman



Published 1997-01-01 in Nucleosides and Nucleotides volume 16:7-9, 955-958 .

Pubmed ID: -
DOI identifier: 10.1080/07328319708006114

Abstract:
The synthesis of all four phosphoramidites of 2’-O-rnethylthiomethyl ribonucleosides and their incorporation into hammerhead ribozymes and influence on nuclease stability and catalytic activity is described.


Entry added on: 2012-06-27 08:54:42.388629, by a user: mark