Modification Summary

2-methylthio-N6-(cis-hydroxyisopentenyl) adenosine

[show modification pathway]


Full name2-methylthio-N6-(cis-hydroxyisopentenyl) adenosine
Short namems2io6A
New Nomenclature2160A
RNAMods abbreviation
HTML abbreviation
Enzymes MiaE (Salmonella typhimurium)
Found in phylogenyEubacteria
Found in RNAtRNA
SMILES codeC/C(CO)=C\CNc3nc(SC)nc2c3ncn2[C@@H]1O[C@H](CO)[C@H](O)C1O

LC-MS Informations

Sum formulaC16O5N5H23S1
Monoisotopic mass397.141989
Average mass397.454563
HRMS mass397.14144
Normalized LC elution time *3,19 (Kellner 2014)
LC elution order/characteristicsafter m6A (Kellner 2014)
Mass transition-132 (Kellner 2014)

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

LC-MS Publications

Title Authors Journal Details PubMed Id DOI
Profiling of RNA modifications by multiplexed stable isotope labelling. Kellner S, Neumann J, Rosenkranz D, Lebedeva S, Ketting RF, Zischler H, Schneider D, Helm M. Chem Commun (Camb). [details] 24567952 -

Download [.mol file for ms2io6A]

Chemical groups contained

heavy atomthiomethyl

Reactions producing 2-methylthio-N6-(cis-hydroxyisopentenyl) adenosine


Last modification of this entry: 2017-07-05 16:54:46.110559
Edited by a user: pboccaletto
Edited content: Changed lc_elution_time, lc_elution_comment, lc_reference and mass_trans.