Modification Summary

5-methoxycarbonylmethyluridine

[show modification pathway]
mcm5U

Summary

Full name5-methoxycarbonylmethyluridine
Short namemcm5U
New Nomenclature521U
RNAMods abbreviation1
HTML abbreviation1
Enzymes ALKBH8 (Homo sapiens)
Trm9 (Saccharomyces cerevisiae)
Found in phylogenyEukaryota
Found in RNAtRNA
SMILES codeC3(OC(CO)C(O)C(O)3)N1C=C(CC(=O)OC)C(=O)NC1(=O)

LC-MS Informations

Sum formulaC12O8N2H16
Monoisotopic mass316.090665
Average mass316.267941
HRMS mass316.090116
Normalized LC elution time * not available
LC elution order/characteristics not available
Mass transition132 (Su 2014); 164 (Su 2014)

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

LC-MS Publications

Title Authors Journal Details PubMed Id DOI
Quantitative analysis of ribonucleoside modifications in tRNA by HPLC-coupled mass spectrometry. Su D, Chan CT, Gu C, Lim KS, Chionh YH, McBee ME, Russell BS, Babu IR, Begley TJ, Dedon PC... Nat Protoc [details] 24625781 -

Download [.mol file for mcm5U]

Chemical groups contained

othercarboxymethyl
othermethylester

Reactions producing 5-methoxycarbonylmethyluridine

Name
cm5U:mcm5U

Reactions starting from 5-methoxycarbonylmethyluridine

Name
mcm5U:mchm5U
mcm5U:mcm5s2U
mcm5U:mcm5Um

Publications

Title Authors Journal Details PubMed Id DOI
Biogenesis and growth phase-dependent alteration of 5-methoxycarbonylmethoxyuridine in tRNA anticodons Sakai Y, Miyauchi K, Kimura S, Suzuki T. Nucleic Acids Res. [details] 26681692 10.1093/nar/gkv1470

Last modification of this entry: 2017-07-05 17:10:04.912754
Edited by a user: pboccaletto
Edited content: Changed lc_reference.