Modification Summary


[show modification pathway]


Full nameN4,2′-O-dimethylcytidine
Short namem4Cm
New Nomenclature04C
RNAMods abbreviationλ
HTML abbreviationλ
Enzymes RsmI (Escherichia coli)
RsmH (Escherichia coli)
Found in phylogenyEubacteria
Found in RNArRNA
SMILES codeC3(OC(CO)C(O)C(O(C))3)N1C=CC(N(C))=NC1(=O)

LC-MS Informations

Sum formulaC11O5N3H17
Monoisotopic mass271.11682
Average mass271.273689
HRMS mass271.116271
Normalized LC elution time *1,20 (Kellner 2014)
LC elution order/characteristicsbetween G and A (Kellner 2014)
Mass transition-146 (Kellner 2014)

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

LC-MS Publications

Title Authors Journal Details PubMed Id DOI
Profiling of RNA modifications by multiplexed stable isotope labelling. Kellner S, Neumann J, Rosenkranz D, Lebedeva S, Ketting RF, Zischler H, Schneider D, Helm M. Chem Commun (Camb). [details] 24567952 -

Download [.mol file for m4Cm]

Chemical groups contained

methyl groupmethyl at O2
methyl groupmethyl at other N

Reactions producing N4,2′-O-dimethylcytidine


Reactions starting from N4,2′-O-dimethylcytidine


Occurrence in PDB structures

PDB-ID chain residue
2i1c y 4OC /1402

Last modification of this entry: 2017-07-05 15:48:22.003697
Edited by a user: pboccaletto
Edited content: Changed lc_elution_time, lc_elution_comment, lc_reference and mass_trans.