Modification Summary


[show modification pathway]


Full nameN2-methylguanosine
Short namem2G
New Nomenclature2G
RNAMods abbreviationL
HTML abbreviationL
Enzymes RlmG (Escherichia coli)
RlmKL (Escherichia coli)
RsmC (Escherichia coli)
RsmD (Escherichia coli)
RsmJ (Escherichia coli)
Trm-G10 (Pyrococcus abyssi)
Trm1 (Saccharomyces cerevisiae)
Trm1 (Aquifex aeolicus)
Trm1 (Pyrococcus horikoshii)
Trm1 (Homo sapiens)
Trm11 (Saccharomyces cerevisiae)
TrmN (Methanocaldococcus jannaschii)
TrmN (Thermus thermophilus)
Found in phylogenyArchaea, Eubacteria, Eukaryota
Found in RNArRNA, snRNA, tRNA
PubChem ID3035422
SMILES codeC3(OC(CO)C(O)C(O)3)N2C=NC1=C2N=C(N(C))NC1=O

LC-MS Information

Sum formulaC11O5N5H15
Monoisotopic mass297.107318
Average mass297.271183
HRMS mass297.106769
Normalized LC elution time * not available
LC elution order/characteristics not available
Mass transition not available

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

Download [.mol file for m2G]

Chemical groups contained

methyl groupmethyl at other N

Reactions producing N2-methylguanosine


Reactions starting from N2-methylguanosine


Occurrence in PDB structures

PDB-ID chain residue
1ehz A 2MG /10
1evv A 2MG /10
1f7u B 2MG /910
1f7v B 2MG /910
1fcw A 2MG /10
1fcw B 2MG /10
1fcw C 2MG /10
1fcw D 2MG /10
1fcw E 2MG /10
1fir A 2MG /6
1fir A 2MG /10
1gix B 2MG /10
1gix C 2MG /10
1jgo B 2MG /10
1jgo C 2MG /10
1jgp B 2MG /10
1jgp C 2MG /10
1jgq B 2MG /10
1jgq C 2MG /10
1mj1 D 2MG /10
1mj1 C 2MG /10
1ml5 B 2MG /10
1ob2 B 2MG /10
1ob5 B 2MG /10
1ob5 D 2MG /10
1ob5 F 2MG /10
1sz1 E 2MG /10
1sz1 F 2MG /10
1tn2 2MG /10
1tra 2MG /10
1ttt D 2MG /10
1ttt E 2MG /10
1ttt F 2MG /10
1wts 2MG /6
1wtt 2MG /6
1yfg 2MG /10
2i1c y 2MG /1207
486d C 2MG /10
4tna 2MG /10
4tra 2MG /10
6tna 2MG /10

Last modification of this entry: 2013-05-10 16:37:03.657799
Edited by a user: magda
Edited content: Kingdom/s added to a modification