Modification Summary

N2,7-dimethylguanosine cap (cap DMG)

[show modification pathway]


Full nameN2,7-dimethylguanosine cap (cap DMG)
Short namem2,7Gpp(pN)
New Nomenclature279553N
RNAMods abbreviation®
HTML abbreviation®
Enzymes Tgs1 (Homo sapiens)
Found in phylogenyEukaryota
Found in RNA
SMILES code[O-]P([O-])(=O)OP([O-])(=O)OC[C@@H]3O[C@H](n2c[n+](C)c1c2N=C(NC)NC1=O)C(O)[C@@H]3O

LC-MS Information

Sum formulaC12H17N5O11P2
Monoisotopic mass469.04
Average mass469.2416
[M+H]+ not available
Product ions not available
Normalized LC elution time * not available
LC elution order/characteristics not available

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

Download [.mol file for m2,7Gpp(pN)]


As with the m7G cap, the m2,7G cap is indistinguishable from any other m7m2G apart from the triester linkage linking it to the rest of the RNA chain, and I'm putting it here separately just for orderliness purpose.

Chemical groups contained

methyl groupmethyl at aromatic N

Reactions producing N2,7-dimethylguanosine cap (cap DMG)


Reactions starting from N2,7-dimethylguanosine cap (cap DMG)


Last modification of this entry: 2014-07-11 15:00:26.710900
Edited by a user: magda
Edited content: Changed formula, formula_html, smile, esc_smile, mass_monoiso, mass_avg and mass_hrms.