Modification Summary

N2,N2,7-trimethylguanosine cap (cap TMG)

[show modification pathway]


Full nameN2,N2,7-trimethylguanosine cap (cap TMG)
Short namem2,2,7Gpp(pN)
New Nomenclature2279553N
RNAMods abbreviationΒΆ
HTML abbreviation
Enzymes Tgs1 (Homo sapiens)
Found in phylogenyEukaryota
Found in RNAsnRNA, snoRNA
SMILES codeCN(C)C3=Nc2c([n+](C)cn2[C@H]1O[C@@H](COP([O-])(=O)O)[C@@H](O)C1O)C(=O)N3

LC-MS Information

Sum formulaC13H19N5O11P2
Monoisotopic mass483.05561
Average mass483.26848
HRMS mass483.05508
Normalized LC elution time * not available
LC elution order/characteristics not available
Mass transition not available

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

Download [.mol file for m2,2,7Gpp(pN)]


m2,2,7G cap is joined to the main chain via a 5'-5' linkage. Apart from sn- and snoRNAs it was found is some human selenoprotein mRNAs.

Chemical groups contained

methyl groupmethyl at aromatic N

Reactions producing N2,N2,7-trimethylguanosine cap (cap TMG)


Last modification of this entry: 2014-12-23 17:42:42.277334
Edited by a user: magda
Edited content: Changed comment.