Modification Summary

1-methylinosine

[show modification pathway]
m1I

Summary

Full name1-methylinosine
Short namem1I
New Nomenclature19A
RNAMods abbreviationO
HTML abbreviationO
Enzymes Trm5 (Saccharomyces cerevisiae)
Found in phylogenyEukaryota
Found in RNAtRNA
PubChem ID65095
SMILES codeC3(OC(CO)C(O)C(O)3)N2C=NC1=C2N=CN(C)C1=O

LC-MS Information

Sum formulaC11O5N4H14
Monoisotopic mass282.0964
Average mass282.2565
[M+H]+283.1042
Product ions151
Normalized LC elution time *1,24 (Kellner 2014)
LC elution order/characteristicsbetween G and A (Kellner 2014)

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

LC-MS Publications

Title Authors Journal Details PubMed Id DOI
Profiling of RNA modifications by multiplexed stable isotope labelling. Kellner S, Neumann J, Rosenkranz D, Lebedeva S, Ketting RF, Zischler H, Schneider D, Helm M. Chem Commun (Camb). [details] 24567952 -
Quantitative analysis of ribonucleoside modifications in tRNA by HPLC-coupled mass spectrometry. Su D, Chan CT, Gu C, Lim KS, Chionh YH, McBee ME, Russell BS, Babu IR, Begley TJ, Dedon PC... Nat Protoc [details] 24625781 -

Download [.mol file for m1I]

Chemical groups contained

methyl groupmethyl at aromatic N
otherketo

Reactions producing 1-methylinosine

Name
I:m1I
m1A:m1I

Reactions starting from 1-methylinosine

Name
m1I:m1Im

Last modification of this entry: 2017-07-05 15:49:42.932655
Edited by a user: pboccaletto
Edited content: Changed lc_elution_time, lc_elution_comment, lc_reference and mass_trans.