Modification Summary

N6-(cis-hydroxyisopentenyl)adenosine

[show modification pathway]
io6A

Summary

Full nameN6-(cis-hydroxyisopentenyl)adenosine
Short nameio6A
New Nomenclature60A
RNAMods abbreviation`
HTML abbreviation`
Enzymes MiaE (Salmonella typhimurium)
Found in phylogenyEubacteria
Found in RNAtRNA
SMILES codeC3(OC(CO)C(O)C(O)3)N2C=NC1=C2N=CN=C1N(CC=C(C)/CO)

LC-MS Information

Sum formulaC15O5N5H21
Monoisotopic mass351.1543
Average mass351.3632
[M+H]+352.1621
Product ions220
Normalized LC elution time *2,59 (Kellner 2014)
LC elution order/characteristicsafter m6A (Kellner 2014)

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

LC-MS Publications

Title Authors Journal Details PubMed Id DOI
Profiling of RNA modifications by multiplexed stable isotope labelling. Kellner S, Neumann J, Rosenkranz D, Lebedeva S, Ketting RF, Zischler H, Schneider D, Helm M. Chem Commun (Camb). [details] 24567952 -

Download [.mol file for io6A]

Chemical groups contained

otherhydroxyl
otherisopentenyl

Reactions producing N6-(cis-hydroxyisopentenyl)adenosine

Name
i6A:io6A

Reactions starting from N6-(cis-hydroxyisopentenyl)adenosine

Name
io6A:ms2io6A

Last modification of this entry: 2017-10-06 16:18:35.791100
Edited by a user: pboccaletto
Edited content: Changed mass_prot.