Modification Summary

5-(isopentenylaminomethyl)-2-thiouridine

[show modification pathway]
inm5s2U

Summary

Full name5-(isopentenylaminomethyl)-2-thiouridine
Short nameinm5s2U
New Nomenclature2583U
RNAMods abbreviation½
HTML abbreviation½
Enzymes
Found in phylogeny
Found in RNA
SMILES codeCC(C)=CCNCC1=CN(C2OC(CO)C(O)C2O)C(=S)NC1=O

LC-MS Information

Sum formulaC15H23N3O5S
Monoisotopic mass357.13583
Average mass357.43084
HRMS mass357.13529
Normalized LC elution time * not available
LC elution order/characteristics not available
Mass transition not available

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

Download [.mol file for inm5s2U]

Comments

5-(isopentenylaminomethyl)uridine and 2-thio-5-(isopentenylaminomethyl)uridine were identified in tRNA of Thermodesulfobacterium commune. Their identities were determined by mass spectrometry and confirmed by chemical synthesis. Data were presented at the tRNA meeting in Banz, Germany (1985) by P.F. Crain, D.R. Phillips, T. Hashizume and F. Widdel. Since then, beside the Banz-meeting abstract, no paper was published about these modified nucleosides.

Reactions producing 5-(isopentenylaminomethyl)-2-thiouridine

Name
nm5s2U:inm5s2U

Last modification of this entry: 2014-06-18 11:07:26.266736
Edited by a user: magda
Edited content: Changed formula.