Modification Summary

N6-hydroxynorvalylcarbamoyladenosine

[show modification pathway]
hn6A

Summary

Full nameN6-hydroxynorvalylcarbamoyladenosine
Short namehn6A
New Nomenclature63A
RNAMods abbreviation
HTML abbreviation
Enzymes
Found in phylogeny
Found in RNA
SMILES codeC3(OC(CO)C(O)C(O)3)N2C=NC1=C2N=CN=C1N(C(=O)NC(C(O)CC)C(=O)O)

LC-MS Informations

Sum formulaC16O8N6H22
Monoisotopic mass426.149911
Average mass426.386836
HRMS mass426.149362
Normalized LC elution time *1,93 (Kellner 2014)
LC elution order/characteristicsbetween A and m6A (Kellner 2014)
Mass transition-132 (Kellner 2014)

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

LC-MS Publications

Title Authors Journal Details PubMed Id DOI
Profiling of RNA modifications by multiplexed stable isotope labelling. Kellner S, Neumann J, Rosenkranz D, Lebedeva S, Ketting RF, Zischler H, Schneider D, Helm M. Chem Commun (Camb). [details] 24567952 -

Download [.mol file for hn6A]

Chemical groups contained

aminoacyl groupnorvalyl
othercarbamoyl
otherhydroxyl

Reactions producing N6-hydroxynorvalylcarbamoyladenosine

Name
A:hn6A

Reactions starting from N6-hydroxynorvalylcarbamoyladenosine

Name
hn6A:ms2hn6A

Publications

Title Authors Journal Details PubMed Id DOI
Structure determination of two new amino acid-containing derivatives of adenosine from tRNA of thermophilic bacteria and archaea. Reddy DM, Crain PF, Edmonds CG, Gupta R, Hashizume T, Stetter KO, Widdel F, McCloskey JA... Nucleic Acids Res [details] 1280806 -

Last modification of this entry: 2017-07-05 16:44:51.077428
Edited by a user: pboccaletto
Edited content: Changed lc_elution_time, lc_elution_comment, lc_reference and mass_trans.