Modification Summary

N6-hydroxymethyladenosine

[show modification pathway]
hm6A

Summary

Full nameN6-hydroxymethyladenosine
Short namehm6A
New Nomenclature68A
RNAMods abbreviationϪ
HTML abbreviationϪ
Enzymes FTO (Homo sapiens)
Found in phylogenyEukaryota
Found in RNAmRNA
SMILES codeOCNc3ncnc2c3ncn2[C@@H]1O[C@H](CO)[C@H](O)C1O

LC-MS Information

Sum formulaC11H15N5O5
Monoisotopic mass297.1073
Average mass297.2708
[M+H]+298.1151
Product ions268/136
Normalized LC elution time * not available
LC elution order/characteristics not available

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

Download [.mol file for hm6A]

Reactions producing N6-hydroxymethyladenosine

Name
m6A:hm6A

Reactions starting from N6-hydroxymethyladenosine

Name
hm6A:f6A

Publications

Title Authors Journal Details PubMed Id DOI
FTO-mediated formation of N(6)-hydroxymethyladenosine and N(6)-formyladenosine in mammalian RNA. Fu Y, Jia G, Pang X, Wang RN, Wang X, Li CJ, Smemo S, Dai Q, Bailey KA, Nobrega MA, Han KL, Cui Q, He C... Nat Commun [details] 23653210 -

Last modification of this entry: 2017-10-06 16:06:47.001047
Edited by a user: pboccaletto
Edited content: Changed mass_prot.