Modification Summary

2-geranylthiouridine

[show modification pathway]
ges2U

Summary

Full name2-geranylthiouridine
Short nameges2U
New Nomenclature21U
RNAMods abbreviationΓ
HTML abbreviationΓ
Enzymes MnmH (Escherichia coli)
Found in phylogenyEubacteria
Found in RNA
SMILES codeC/C(C)=C\CCC(\C)=C\CSC1=NC(=O)C=CN1[C@@H]2O[C@H](CO)[C@H](O)C2O

LC-MS Information

Sum formulaC19H28N2O5S
Monoisotopic mass396.17187
Average mass396.5078
HRMS mass396.17134
Normalized LC elution time * not available
LC elution order/characteristics not available
Mass transition not available

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

Download [.mol file for ges2U]

Comments

An intermediate in the synthesis of cmnm5ges2U and mnm5ges2U.

Chemical groups contained

sulphurthio
hydrocarbongeranyl

Reactions producing 2-geranylthiouridine

Name
s2U:ges2U

Reactions starting from 2-geranylthiouridine

Name
ges2U:cmnm5ges2U
ges2U:nm5ges2U

Publications

Title Authors Journal Details PubMed Id DOI
A gain of function mutation in a protein mediates production of novel modified nucleosides. Chen P, Crain PF, Nasvall SJ, Pomerantz SC, Bjork GR... EMBO J [details] 15861125 -
Discovery and biological characterization of geranylated RNA in bacteria. Dumelin CE, Chen Y, Leconte AM, Chen YG, Liu DR... Nat Chem Biol [details] 22983156 -

Last modification of this entry: 2014-04-01 17:51:43.268706
Edited by a user: magda
Edited content: RNA type/s added to a modification