Modification Summary

5-carboxymethylaminomethyl-2-geranylthiouridine

[show modification pathway]
cmnm5ges2U

Summary

Full name5-carboxymethylaminomethyl-2-geranylthiouridine
Short namecmnm5ges2U
New Nomenclature2151U
RNAMods abbreviationf
HTML abbreviationf
Enzymes MnmH (Escherichia coli)
Found in phylogenyEubacteria
Found in RNAtRNA
SMILES codeO=C(O)CNCC1=CN(C(=NC1=O)SC\C=C(/C)CC\C=C(/C)C)[C@@H]2O[C@H](CO)[C@H](O)C2O

LC-MS Information

Sum formulaC22H33N3O7S
Monoisotopic mass483.2039
Average mass483.58604
HRMS mass483.20337
Normalized LC elution time
LC elution order/characteristics
LC literature references
MS Data File
MS/MS Data File
MS/MS/MS (base ion) Data File
MS literature references

Download [.mol file for cmnm5ges2U]

Comments

Present in position 34 in a small fraction of E. coli tRNAGlnUUG.

Chemical groups contained

aminoalkylcarboxymethylaminomethyl
sulphurthio
hydrocarbongeranyl

Reactions producing 5-carboxymethylaminomethyl-2-geranylthiouridine

Name
cmnm5s2U:cmnm5ges2U
ges2U:cmnm5ges2U

Reactions starting from 5-carboxymethylaminomethyl-2-geranylthiouridine

Name
cmnm5ges2U:nm5ges2U

Publications

Title Authors Journal Details PubMed Id DOI
A gain of function mutation in a protein mediates production of novel modified nucleosides. Chen P, Crain PF, Nasvall SJ, Pomerantz SC, Bjork GR... EMBO J [details] 15861125 -
Discovery and biological characterization of geranylated RNA in bacteria. Dumelin CE, Chen Y, Leconte AM, Chen YG, Liu DR... Nat Chem Biol [details] 22983156 -

Last modification of this entry: 2014-04-01 17:51:43.505695
Edited by a user: magda
Edited content: RNA type/s added to a modification