Modification Summary

3-(3-amino-3-carboxypropyl)pseudouridine

[show modification pathway]
acp3Y

Summary

Full name3-(3-amino-3-carboxypropyl)pseudouridine
Short nameacp3Y
New Nomenclature309U
RNAMods abbreviationÞ
HTML abbreviationÞ
Enzymes
Found in phylogeny
Found in RNA
SMILES codeNC(CCN1C(=O)NC=C(C2OC(CO)C(O)C2O)C1=O)C(O)=O

LC-MS Information

Sum formulaC13H19N3O8
Monoisotopic mass345.1172
Average mass345.3093
[M+H]+346.125
Product ions214
Normalized LC elution time * not available
LC elution order/characteristics not available

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

Download [.mol file for acp3Y]

Comments

acp3Y is accumulated when the Nep1 enzyme is absent. The enzyme catalyzing the acp3Y formation in S. cerevisiae is still unknown.

Reactions producing 3-(3-amino-3-carboxypropyl)pseudouridine

Name
Y:acp3Y
acp3U:acp3Y

Publications

Title Authors Journal Details PubMed Id DOI
The Bowen-Conradi syndrome protein Nep1 (Emg1) has a dual role in eukaryotic ribosome biogenesis, as an essential assembly factor and in the methylation of Psi1191 in yeast 18S rRNA. Meyer B, Wurm JP, Kotter P, Leisegang MS, Schilling V, Buchhaupt M, Held M, Bahr U, Karas M, Heckel A, Bohnsack MT, Wohnert J, Entian KD Nucleic Acids Res [details] 20972225 -

Last modification of this entry: 2013-05-10 16:36:54.406188
Edited by a user: magda
Edited content: Kingdom/s added to a modification