Modification Summary


[show modification pathway]


Full nameinosine
Short nameI
New Nomenclature9A
RNAMods abbreviationI
HTML abbreviationI
Enzymes Tad1 (Saccharomyces cerevisiae)
Tad1 (Homo sapiens)
Tad2 (Saccharomyces cerevisiae)
Tad3 (Saccharomyces cerevisiae)
TadA (Escherichia coli)
TadA (Arabidopsis thaliana)
Found in phylogenyEubacteria, Eukaryota
Found in RNAtRNA
PubChem ID6021

LC-MS Informations

Sum formulaC10O5N4H12
Monoisotopic mass268.080769
Average mass268.229496
HRMS mass268.08022
Normalized LC elution time *0,95 (Kellner 2014, Kellner 2014)
LC elution order/characteristicsbetween U and G (Kellner 2014, Kellner 2014)
Mass transition-132 (Kellner 2014, Kellner 2014, Su 2014)

* normalized to guanosine (G), measured with a RP C-18 column with acetonitrile/ammonium acetate as mobile phase.

LC-MS Publications

Title Authors Journal Details PubMed Id DOI
Profiling of RNA modifications by multiplexed stable isotope labelling. Kellner S, Neumann J, Rosenkranz D, Lebedeva S, Ketting RF, Zischler H, Schneider D, Helm M. Chem Commun (Camb). [details] 24567952 -
Quantitative analysis of ribonucleoside modifications in tRNA by HPLC-coupled mass spectrometry. Su D, Chan CT, Gu C, Lim KS, Chionh YH, McBee ME, Russell BS, Babu IR, Begley TJ, Dedon PC... Nat Protoc [details] 24625781 -
Absolute and relative quantification of RNA modifications via biosynthetic isotopomers. Kellner S, Ochel A, Thuring K, Spenkuch F, Neumann J, Sharma S, Entian KD, Schneider D, Helm M... Nucleic Acids Res [details] 25129236 -

Download [.mol file for I]

Chemical groups contained


Reactions producing inosine


Reactions starting from inosine


Occurrence in PDB structures

PDB-ID chain residue
1f7u B I /934
1f7v B I /934
1saq A I /102
1saq B I /110
1saq C I /202
1saq D I /210
1saq E I /302
1xnq X I /34
1xnr X I /34
1zft B I /8
2bcz B I /8
333d A I /5
409d A I /4
409d B I /12
409d C I /20
409d D I /28
409d E I /36
409d F I /44

Last modification of this entry: 2017-07-05 15:40:02.364114
Edited by a user: pboccaletto
Edited content: Changed lc_elution_time, lc_elution_comment, lc_reference and mass_trans.