Building block Summary

5-hydroxycytidine

IUPAC Name 5-hydroxycytidine
CAS number 39638-73-8

Natural occurring structure:

Building block structure:

Building block characteristics:

  • 2-nitrobenzyl: photodeprotection with tungsten slide projector lamp (lambda >300 nm) 

  • N’,N’-dimethylformamidino: base labile group 

  • cyanoethyloxy‑N,N‑diisopropylphophoramidite : n/a 
  • dimethoxytrityl: acide labile group 
  • tert‑butyldimethylsilyl: fluoride labile 


Publications

Title Authors Journal Details PubMed Id DOI
Synthesis, base pairing properties and trans-lesion synthesis by reverse transcriptases of oligoribonucleotides containing the oxidatively damaged base 5-hydroxycytidine. Kupfer PA, Leumann CJ... Nucleic Acids Res [details] 21852326 -

Last modification of this entry: 2012-09-26 18:46:31.207250
Edited by a user: mark
Edited content: Changed papers.