Building block Summary


IUPAC Name 5-methylaminomethyl-2-thiouridine
CAS number 32860-54-1

Natural occurring structure:

Building block structure:

Building block characteristics:

  • cyanoethyloxy‑N,N‑diisopropylphophoramidite : n/a 
  • dimethoxytrityl: acide labile group 
  • tert‑butyldimethylsilyl: fluoride labile 
  • trifluoracetyl: base labile  


Title Authors Journal Details PubMed Id DOI
Synthesis and Characterization of the Native Anticodon Domain of E. coli tRNALys:  Simultaneous Incorporation of Modified Nucleosides mnm5s2U, t6A, and Pseudouridine Using Phosphoramidite Chemistry Mallikarjun Sundaram, Pamela F. Crain, and Darrell R. Davis J. Org. Chem. [details] 10970299 10.1021/jo000338b
Introduction of hypermodified nucleotides in RNA. Davis DR, Bajji AC Methods Mol Biol [details] 15333904 -

Last modification of this entry: 2012-05-31 19:12:53.624908
Edited by a user: mark
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