Building block Summary

N6,N6,2'-O-trimethyladenosine

IUPAC Name N6,N6,2'-O-trimethyladenosine
CAS number 30891-53-3

Natural occurring structure:

Building block structure:

Building block characteristics:

  • cyanoethyloxy‑N,N‑diisopropylphophoramidite : n/a 
  • dimethoxytrityl: acide labile group 
  • triisopropyloxymethyl: fluoride labile 


Publications

Title Authors Journal Details PubMed Id DOI
The synthesis of 2'-O-[(Triisopropylsilyl)oxy] methyl (TOM) phosphoramidites of methylated ribonucleosides (m1G, m2G, m22G, m1I, m3U, m4C, m6A, m62A) for use in automated RNA solid-phase synthesis HÖBARTNER Claudia ; KREUTZ Christoph ; FLECKER Elke ; OTTENSCHLÄGER Elke ; PILS Werner ; GRUBMAYR Karl ; MICURA Ronald ; Monatshefte fuer Chemie [details] - -
Synthesis of 2′-O-[(Triisopropylsilyl)oxy]methyl (= tom)-Protected Ribonucleoside Phosphoramidites Containing Various Nucleobase Analogues Porcher S, Pitsch S. HELVETICA CHIMICA ACTA [details] - 10.1002/hlca.200590209

Last modification of this entry: 2012-05-31 17:13:08.044877
Edited by a user: mark
Edited content: No fields changed.