Building block Summary


IUPAC Name 2-thiouridine
CAS number 20235-78-3

Natural occurring structure:

Building block structure:

Building block characteristics:

  • cyanoethyloxy‑N,N‑diisopropylphophoramidite : n/a 
  • dimethoxytrityl: acide labile group 
  • tert‑butyldimethylsilyl: fluoride labile 


Title Authors Journal Details PubMed Id DOI
Site-selected introduction of modified purine and pyrimidine ribonucleosides into RNA by automated phosphoramidite chemistry. Agris PF, Malkiewicz A, Kraszewski A et al. Biochimie [details] 7599270 10.1016/0300-9084(96)88115-6
Synthesis and studies on the effect of 2-thiouridine and 4-thiouridine on sugar conformation and RNA duplex stability. Kumar RK, Davis DR Nucleic Acids Res [details] 9092639 10.1093/nar/25.6.1272

Last modification of this entry: 2012-06-27 09:04:48.960727
Edited by a user: mark
Edited content: Changed building_block_image_file.